Teenager Natalie Morton died from a malignant tumour in her chest and not from a reaction to the cervical cancer jab.
Deputy coroner for Coventry Louise Hunt told the 14-year-old's parents that the current indication was that the vaccine was not a contributing factor in her death.
Opening and adjourning the inquest at Coventry Magistrates' Court, she said: "It appears that Natalie died from a tumour in her chest involving her heart and her lungs."
Natalie collapsed less than two hours after being given a cervical cancer vaccination at Coventry's Blue Coat Church of England School on Monday.
The deputy coroner for Coventry heard that Natalie collapsed in a corridor at the school around 75 minutes after being given her injection.
Natalie's mother Elaine Bullock and stepfather Andrew Bullock, paid tribute the 14-year-old outside the court.
They said she was a "kind and fun-loving teenager with a beautiful smile".
Mr Bullock said: "Natalie was a wonderful daughter, sister and granddaughter. She was kind, fun-loving and had a beautiful smile.
"Natalie had a strong personal faith in God. We know that she has gone to heaven to be with her saviour, Jesus."
He added: "We now know that Natalie's death was the result of a serious underlying medical condition and most probably nothing to do with the vaccine that she had at school on Monday."
