Julian Assange will not be granted diplomatic status as a way of breaking the deadlock over his presence in the UK.
The Foreign Office rejected a request from the Ecuadorian government to grant the Wikileaks founder protection.
Mr Assange, 46, has been living in the London embassy of the south American country for five-and-a-half years after being granted political asylum as he fought sex-related claims in Sweden.
An FCO spokesman said: "The Government of Ecuador recently requested diplomatic status for Mr Assange here in the UK.
"The UK did not grant that request, nor are we in talks with Ecuador on this matter.
"Ecuador knows that the way to resolve this issue is for Julian Assange to leave the embassy to face justice."
Swedish prosecutors have dropped their investigation into allegations against Mr Assange, which included a claim of rape.
But he fears he will be extradited to the United States if he leaves the embassy, and that there is a sealed indictment ordering his arrest.
Julian Assange - In pictures
Ecuador's foreign minister, Maria Fernanda Espinosa, said: "No solution will be achieved without international cooperation and the cooperation of the United Kingdom, which has also shown interest in seeking a way out."
A United Nations panel concluded in 2016 that Mr Assange was under arbitrary detention.
A statement by Mr Assange's legal team said: "The UN ruling, issued almost two years ago, is crystal clear in its language. Mr Assange is unlawfully and arbitrarily detained by the UK authorities and must be released.
"The UK should not permit itself to be intimidated by the Trump administration's public threats to 'take down' Mr Assange."
