Jarrod Bowen is again sidelined by a heel injury, while Vladimir Coufal is still recovering from a hernia operation.
“We have a few limping but you expect that after a tough game,” said manager David Moyes on Friday.
“We'll assess them all this morning and see how they are. It's a bit early to know a lot about the team."
Andriry Yarmolenko has been well-suited to an impact role and, even despite his recent goals, is once again on the bench for the Hammers.
Moyes looks to have gone for a back five, with Arthur Masuaku into the side at left wing-back. Said Benrahma is preferred to Nikola Vlasic.
West Ham XI: Fabianski, Johnson, Dawson, Zouma, Cresswell, Masuaku, Rice, Soucek, Lanzini, Benrahma, Antonio
Subs: Areola, Diop, Fornals, Vlasic, Fredericks, Král, Perkins, Yarmolenko, Noble
Where: Tottenham Hotspur Stadium, London
When: Sunday, March 20, 16.30
TV: Sky Sports
Referee: Anthony Taylor
